Analysis of risk factors for atrial fibrillation in elderly Chinese patients with severe valvular heart disease
10.3760/cma.j.issn.0254-9026.2022.09.003
- VernacularTitle:老年重度瓣膜性心脏病合并心房颤动患者的危险因素分析
- Author:
Xiang WANG
1
;
Chenxi XIA
;
Xuyang MENG
;
Ying GUO
;
Haiyan WANG
;
You ZHONG
;
Haiyan XU
;
Yongjian WU
;
Fang WANG
Author Information
1. 北京医院心内科 国家老年医学中心 中国医学科学院老年研究院，北京 100730
- Keywords:
Valvular heart disease;
Atrial fibrillation;
Left atrial anteroposterior diameter;
Left ventricular end-diastolic diameter
- From:
Chinese Journal of Geriatrics
2022;41(9):1032-1036
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the risk factors for atrial fibrillation(AF)in elderly Chinese patients with severe valvular heart disease(VHD).Methods:This was a cross-sectional study and consecutively enrolled 978 elderly patients with severe VHD diagnosed in 18 Class A tertiary hospitals across the country from September 2021 to March 2022, including 322(32.9%)patients with concurrent AF.Clinical and echocardiographic data were collected to analyze the risk factors for AF.Results:Among VHD patients, compared with the non-AF group, the AF group was older, had a higher female ratio, higher diastolic blood pressure, higher proportions with cerebrovascular disease and chronic kidney disease, lower serum low density lipoprotein cholesterol and higher serum creatinine, amino-terminal A-type natriuretion peptide and glycosylated hemoglobin.As for echocardiographic parameters, the left atrial diameter was larger, the left ventricular end-diastolic diameter, interventricular septum thickness, and left ventricular posterior wall thickness were smaller in the AF group than in the non-AF group.All of the differences were statistically significant(all P<0.05). The results of multivariate Logistic regression analysis showed that the left atrial anteroposterior diameter increased( OR=1.166, P<0.01), the left ventricular end-diastolic diameter decreased( OR=0.929, P<0.01), and advanced age( OR=1.051, P<0.05)was an independent risk factor for elderly VHD patients with concurrent AF. Conclusions:In elderly patients with severe VHD, advanced age, an increased left atrial anteroposterior diameter, and a decreased left ventricular end-diastolic diameter were independently associated with AF.Therefore, evaluation of cardiac structure and regular follow-up should be performed in elderly patients with severe VHD for early intervention to reduce the incidence of AF.
