Reference value of lumbar spine bone mineral density and regional differences based on quantitative CT examination in healthy adult female in China
10.3760/cma.j.cn115624-20220321-00186
- VernacularTitle:基于定量CT的中国健康成年女性腰椎骨密度正常参考值及地区差异
- Author:
Ying JIN
1
;
Kaiping ZHAO
;
Jian QU
;
Xia DU
;
Yongli LI
;
Shuang CHEN
;
Yan WU
;
Chunwei WU
;
Guobin HONG
;
Yong LU
;
Yuqin ZHANG
;
Xiao MA
;
Jing LU
;
Xigang XIAO
;
Xiangyang GONG
;
Zehong YANG
;
Wei CHEN
;
Miaomiao AN
;
Ziyun WANG
;
Siping NIE
;
Lü YINGRU
;
Jianbo GAO
;
Shaolin LI
;
Yuehua LI
;
Qiang ZENG
;
Xiaoguang CHENG
;
Limei RAN
Author Information
1. 贵州医科大学公共卫生学院，贵阳 550025
- Keywords:
Osteoporosis;
Healthy adult female;
Quantitative CT;
Bone mineral density
- From:
Chinese Journal of Health Management
2022;16(9):610-615
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the normal reference value of lumbar bone mineral density (BMD) under quantitative CT (QCT) in Chinese healthy adult females and to explore the regional differences.Methods:Total of 35 431 healthy women who met the inclusion criteria of Chinese health quantitative CT big data program were selected in this study. The BMD of the central plane of L 1 and L 2 vertebrae was measured by Mindways′s QCT system, and the mean value was taken. One-way analysis of variance was used to compare the BMD differences of lumbar vertebrae in women of different ages and regions. The subjects were grouped by an age interval of 10 years, and the level of BMD in different regions of the same age group were compaired. Results:The peak BMD of Chinese healthy adult women appeared in the age group of 20-29 years (Northeast China(183.01±24.58) mg/cm 3, North China (188.93±24.80) mg/cm 3, East China (187.54±27.71) mg/cm 3, South China (186.22±33.72) mg/cm 3, Central China (176.33±24.91) mg/cm 3, Southwest China(182.25±28.00) mg/cm 3), and then it decreased with age. The level of BMD in different regions decreased with the age. Before the age of 70 years, BMD in Central and Southwest China was always at a low level((176.23±24.91) to (90.38±28.12) mg/cm 3, 182.25±28.00 to (88.55±25.68) mg/cm 3), lower than those in Northeast China ((183.01±24.58) to (99.69±27.85) mg/cm 3), North China ((188.93±24.80) to (95.89±26.12) mg/cm 3), East China ((187.54±27.71) to (95.65±27.86) mg/cm 3). After 70 years of age, BMD tended to be the same in different regions ( P>0.05). The BMD values in Central China and Southwest China were similar in the age group of 40-60 years ( P>0.05). The BMD values in the health adult femles in the age group of 60 years in different regions of Chinawere all lower than those of bone mass abnormality (all P<0.05). The detection rate of osteoporosis in females over 50 years was the highest in Southwest China (25.65%) and it was the lowest in North China (17.30%). Conclusions:This study establishes reference values of BMD under QCT in healthy Chinese women, which can be used as a reference basis for identifying women with low BMD who are at risk of osteoporosis. The BMD value is the lowest in Southwest China and the highest in South China.
