Normal reference and regional variation of spinal bone mineral density under the quantitative CT in Chinese male population
10.3760/cma.j.cn115624-20220516-00371
- VernacularTitle:中国成年男性人群脊柱定量CT骨密度参考值和地区差异
- Author:
Liuping CHEN
1
;
Jian ZHAI
;
Limei RAN
;
Yongli LI
;
Lü YINGRU
;
Yan WU
;
Shaolin LI
;
Hanqi WANG
;
Yaling PAN
;
Tongtong CHEN
;
Lü HAIYING
;
Kaiping ZHAO
;
Yuqin ZHANG
;
Xiao MA
;
Jing LU
;
Xigang XIAO
;
Xiangyang GONG
;
Zehong YANG
;
Wei CHEN
;
Jianbo GAO
;
Yuehua LI
;
Xia DU
;
Zhenlin LI
;
Qiang ZENG
;
Xiaoguang CHENG
;
Shuang CHEN
;
Jing WU
;
Yong LU
Author Information
1. 上海交通大学医学院附属瑞金医院放射科，上海 200025
- Keywords:
Osteoporosis;
Bone mineral density;
Male;
Quantitative computed tomography
- From:
Chinese Journal of Health Management
2022;16(9):604-609
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the normal reference values of spinal bone mineral density measured by quantitative computed tomography (QCT) and the differences of bone mineral density (BMD) in different regions of in Chinese adult males.Methods:Men who underwent low-dose CT lung scan for cancer screening in regions of Northeast, North, East, South, Central and Southwest of China from January 2018 to December 2019 were selected. And the lumbar vertebrae BMD values in the male subjects were measured by the QCT system (Mindways Software, Inc.). The mean BMD values and their decline rates were calculated at an age interval of 10 years, and the prevalence of osteoporosis was calculated according to the American College of Radiology spine QCT osteoporosis diagnostic criteria.Results:A total of 50 682 males with a mean age of (50.22±12.79) years (ranged 20 to 98 years) were included in this study. The peak BMD of (173.11±28.56) mg/cm 3 in the healthy Chinese adult male population appeared in the age group of 20 to 29 years and then declined with age. Before the age of 70 years, the BMD was relatively higher in males in South China, and it was lower in Central China and Southwest China, and it was intermediate in Northeast, North and East of China, with statistically significant differences. There was no significant differences in BMD in the males in the two age groups of 70 to 79 years and 80 and older among the regions in China. The overall decline rate of spinal BMD in Chinese males under QCT was about 46.92% over the lifetime, and it declined obviouslyin the 40-49 age group. The overall prevalence of osteoporosis in Chinese male population aged 50 years and above was approximately 11.42%, with the highest prevalence in Southwest China and Central China (14.72% and 13.87%, respectively) and the lowest in North China and South China (8.53% and 7.71%, respectively). Conclusions:A reference of lumbar spine BMD values for healthy males in China based on QCT is established. BMD values were highest in South China and Lowest in Central China.
