Advances in molecular imaging by targeting macrophages of atherosclerosis vulnerable plaques

VernacularTitle:基于巨噬细胞的动脉粥样硬化易损斑块靶向成像的研究进展
Author: Caiyun SHI ¹ ; Lingjie WANG ; Hua ZHANG
Author Information

1. 山西医科大学医学影像学院，太原　030000
Keywords: Plaque, atherosclerotic; Molecular imaging; Macrophages; Trends
From: Chinese Journal of Nuclear Medicine and Molecular Imaging 2022;42(8):499-503
CountryChina
Language:Chinese
Abstract: Vulnerable plaque rupture is the leading cause of acute cardiovascular diseases. Macrophages are main inflammatory cells closely related to the rupture of vulnerable plaques. Early diagnosis of vulnerable plaque can reduce the mortality of acute cardiovascular diseases. With the development of molecular imaging, the possibility for early identification of vulnerable plaques may come true. This review summarizes the changes of molecular markers of macrophages in vulnerable plaques and the molecular probes that can target macrophages.