Vibrio Vulnificus Sepsis.
- Author:
Dong Min KIM
1
;
Su Jin HONG
Author Information
1. Department of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea. drongkim@chosun.ac.kr
- Publication Type:Review
- Keywords:
Vibrio vulnificus;
Sepsis;
Antibiotics
- MeSH:
Anti-Bacterial Agents;
Debridement;
Early Diagnosis;
Gastroenteritis;
Humans;
Iron;
Liver Diseases;
Risk Factors;
Sepsis;
Soft Tissue Infections;
Vibrio;
Vibrio vulnificus;
Wound Infection
- From:Korean Journal of Medicine
2012;82(6):671-679
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Vibrio vulnificus (V. vulnificus) is a halophilic motile, gram-negative rod which can cause fatal human infections. The spectrum of illness caused by V. vulnificus is gastroenteritis, primary sepsis, and wound infection. Most of patients infected with V. vulnificus have at least one risk factor such as chronic liver diseases, immunocompromiased hosts, hematologic disorders characterized by elevated iron level. V. vulnificus infection is suspected by clinical and epidemiological history. Radiological studies of affected lesions are helpful to diagnosis of necrotizing soft tissue infection. The definitive diagnosis is made by the isolation of V. vulnificus from blood and wound cultures. The mortality of V. vulnificus primary sepsis is above 50%, so early diagnosis, early surgical debridement and administration of appropriate antibiotics is essential.
