The application of transjugular liver biopsy in patients with unexplained liver disease
10.3760/cma.j.cn113884-20220324-00126
- VernacularTitle:经颈静脉肝内穿刺活检对不明原因肝病患者的应用价值
- Author:
Wenguang ZHANG
1
;
Xianwei QI
;
Jingqiang ZHANG
;
Zhenhua TIAN
;
Pengfei CHEN
;
Xueliang ZHOU
;
Fangzheng LI
;
Yong NIU
;
Jianzhuang REN
;
Xinwei HAN
Author Information
1. 郑州大学第一附属医院放射介入科，郑州 450052
- Keywords:
Biopsy, needle;
Liver diseases;
Hepatic venous pressure gradient;
Portal areas
- From:
Chinese Journal of Hepatobiliary Surgery
2022;28(9):651-655
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical value of transjugular liver biopsy (TJLB) in patients with unexplained liver disease complicated with massive ascites or coagulopathy.Methods:A retrospective analysis was performed from patients underwent TJLB in the First Affiliated Hospital of Zhengzhou University, Zhoukou Central Hospital, Shangqiu First People's Hospital and Jincheng People's Hospital from March 2015 to January 2022 due to unexplained liver disease complicated with massive ascites or coagulopathy. A total of 37 patients were included, including 21 males and 16 females, aged (53.5±11.9) years. According to different puncture points, the patients were divided into two groups: transhepatic right vein TJBL and transhepatic middle vein TJBL. The obtained liver tissue sampling effect, puncture times, complications were analyzed.Results:The success rate of TJLB was 97.3%(36/37). Thirty-six patients were able to obtain more than three segments of liver tissue and obtain histological diagnosis, and the pathological diagnosis rate was 100.0%(36/36). The number of puncture times, the amount of hepatic tissue and the number of portal areas in the right hepatic vein group (21 cases) were (3.7±0.9), (3.7±0.7) and (6.5±0.9) respectively, and those in the middle hepatic vein group (15 cases) were (3.7±0.7), (3.7±0.7) and (6.3±0.8) respectively. There were no significant differences between the two groups (all P>0.05). Conclusion:TJLB is safe and feasible for patients with unexplained liver disease complicated with massive peritoneal effusion and coagulopathy. Good liver tissue specimens can be obtained by TJLB from both right hepatic vein and middle hepatic vein.
