Research progress on the mechanism of hepatocarcinogenesis and development in tumor acidic environment
10.3760/cma.j.cn113884-20220313-00105
- VernacularTitle:肿瘤酸性微环境下肝细胞癌发生发展机制的研究进展
- Author:
Boshi WANG
1
;
Cheng JIN
Author Information
1. 江南大学附属医院肝胆外科,无锡 214122
- Keywords:
Carcinoma, hepatocellular;
Tumor microenvironment;
Mechanism
- From:
Chinese Journal of Hepatobiliary Surgery
2022;28(8):632-636
- CountryChina
- Language:Chinese
-
Abstract:
Primary hepatocellular carcinoma (HCC) is one of the high-risk solid tumors in China. Although there has been more comprehensive progress on HCC caricinogenesis, migration and invasion, the 5-year survival is still poor. In recent years, it has been identified that tumor acidic microenvironment may promote the occurrence and development of hepatocellular carcinoma. In this paper, combined with the latest research at home and abroad, the research progress on the occurrence and development of hepatocellular carcinoma under an acidic environment was reviewed.