Application prospect of fatty liver in liver transplantation

VernacularTitle:脂肪肝在肝移植中的应用前景
Author: Yang XIAO ¹ ; Mingli YIN ; Xinyuan WEN
Author Information

1. 济宁医学院临床医学院，济宁　272067
Keywords: Fatty liver; Liver transplantation; Complications; Marginal donor livers; Ischemia-reperfusion injury
From: Chinese Journal of Hepatobiliary Surgery 2022;28(8):628-632
CountryChina
Language:Chinese
Abstract: Currently liver transplantation is the most effective treatment options for patients with end-stage liver disease, but the lack of donor livers limits the development of liver transplantation. With the increasing usage of marginal donor liver such as fatty donor liver, therefore how to make marginal donor liver play a better role has become a new research hotspot. Although the use of fatty liver as a donor can effectively alleviate the contradiction between recipient demand and donor organ shortage, the risk of early post-transplant graft dysfunction also increases. As donor of fatty liver, the degree of steatoidosis should be moderate or below as far as possible, which significantly reduces postoperative complications and promote the recovery of recipients. Meanwhile, it is essential to monitor the lipid indicators post the surgery, and drug intervention can be added if necessary, which may improve the function of the graft.