Updates and prospect of neoadjuvant radiotherapy for early breast cancer
10.3760/cma.j.cn113030-20210823-00056
- VernacularTitle:早期乳腺癌新辅助放疗现状与展望
- Author:
Xueer WANG
1
;
Jie JIANG
;
Wei HUANG
;
Baosheng LI
Author Information
1. 山东第一医科大学,济南 250117
- Keywords:
Breast neoplasms;
Radiotherapy, adjuvant;
Neoadjuvant radiotherapy
- From:
Chinese Journal of Radiation Oncology
2022;31(12):1174-1178
- CountryChina
- Language:Chinese
-
Abstract:
Adjuvant radiotherapy has become an important part of the standard treatment for breast cancer. Compared with the traditional postoperative radiotherapy, neoadjuvant radiotherapy has the theoretical advantages of more accurate target delineation, optimization of radiation strategy for breast reconstruction, increase of breast conservation surgery with tumor down-staging and avoiding breast surgery by improving pathological complete response rate, which have been confirmed by recent clinical research. Prospective studies are still needed for the optimal target delineation, dose fractionation, radiation-surgery interval, and combination with systemic therapies, aiming to provide the optimal treatment option for patients with early breast cancer.