Simultaneous integrated tumor bed boost during whole breast radiotherapy in breast cancer patients after breast-conserving surgery: a review of the current evidence
10.3760/cma.j.cn113030-20220110-00013
- VernacularTitle:乳腺癌保乳术后全乳放疗瘤床同步补量研究进展
- Author:
Danqiong WANG
1
;
Shulian WANG
Author Information
1. 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科，北京 100021
- Keywords:
Breast neoplasms;
Radiotherapy;
Breast-conserving surgery;
Sequential boost;
Simultaneous integrated boost
- From:
Chinese Journal of Radiation Oncology
2022;31(11):1070-1075
- CountryChina
- Language:Chinese
-
Abstract:
Radiotherapy is an important treatment modality in breast-conserving therapy of breast cancer. At present, hypofractionation has become the preferred dose schedule for whole breast irradiation. Tumor bed boost can further improve the local control, and sequential boost is recommended for high-risk patients. The widespread application of intensity-modulated radiation therapy provides dosimetric advantages and practical convenience for simultaneous integrated boost. In this review, the indications of tumor bed boost and recent research progress on simultaneous integrated boost were summarized, specifically focusing on the safety and efficacy of simultaneous integrated boost during conventional fractionated or hypofractionated whole breast radiotherapy. Ongoing phase Ⅲ randomized clinical trials of simultaneous integrated boost during hypofractionated whole breast radiotherapy were also illustrated.
