Research progress on the definition of intermediate risk factors and postoperative adjuvant therapy for early cervical cancer
10.3760/cma.j.cn113030-20210712-00255
- VernacularTitle:早期宫颈癌术后中危因素定义及辅助治疗的研究进展
- Author:
Yang SUN
1
;
Ya'nan CHEN
Author Information
1. 张家港市第一人民医院肿瘤科，苏州 215600
- Keywords:
Uterine cervical neoplasms;
Radical hysterectomy;
Intermediate risk factors;
Adjuvant therapy
- From:
Chinese Journal of Radiation Oncology
2022;31(10):961-965
- CountryChina
- Language:Chinese
-
Abstract:
Cervical cancer is still a common gynecolgical tumor in China. Radical surgery is often the first choice for the treatment of early stage cervical cancer (FIGO stage ⅠB-ⅡA), and postoperative pathological examination often has adverse prognostic factors affecting the survival. According to the NCCN guidelines, patients with cervical cancer who meet Sedlis criteria and have intermediate-risk factors (lymphatic vascular space involvement, tumor size or deep interstitial infiltration) are recommended to receive concurrent chemotherapy with postoperative pelvic external irradiation ± cisplatin. However, the diagnostic criteria, indications and methods of adjuvant therapy for patients with intermediate risk factors after early cervical cancer surgery are still controversial. In this article, research progress on the definition of intermediate risk factors for early cervical cancer after radical hysterectomy and adjuvant treatment was mainly reviewed.
