Research progress on bevacizumab in the treatment of radiation-induced brain necrosis
10.3760/cma.j.cn113030-20210412-00146
- VernacularTitle:贝伐珠单抗治疗放射性脑坏死研究进展
- Author:
Shuai HAN
1
;
Wenyan WANG
;
Huandi ZHOU
;
Xiaoying XUE
Author Information
1. 河北医科大学第二附属医院放疗科,石家庄 050000
- Keywords:
Radiation-induced brain necrosis;
Bevacizumab;
Radiotherapy;
Brain neoplasms
- From:
Chinese Journal of Radiation Oncology
2022;31(8):737-740
- CountryChina
- Language:Chinese
-
Abstract:
Radiation-induced brain necrosis (RIBN) is a serious late and irreversible complication after radiation therapy for primary or secondary brain tumors as well as head and neck tumors, and there is no effective treatment. In recent years, bevacizumab has been increasingly applied in the treatment of RIBN, which has been proven to yield certain efficacy and improve patient survival. However, the optimal treatment timing and regimen have been controversial and lack of basic consensus. In this article, research progress on these issues was briefly reviewed.