Preliminary imaging study on the distribution of female Volumetric Breast Density
10.3760/cma.j.cn112271-20220527-00229
- VernacularTitle:女性乳腺体积密度及分布的影像学初步研究
- Author:
Jiahao WANG
1
;
Rui QIU
;
Ankang HU
;
Tianliang KANG
;
Zechen FENG
;
Yantao NIU
;
Junli LI
Author Information
1. 清华大学工程物理系 粒子技术与辐射成像教育部重点实验室，北京 100084
- Keywords:
Mammography;
Volumetric breast density;
Glandularity
- From:
Chinese Journal of Radiological Medicine and Protection
2022;42(10):806-811
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To describe the distribution of volumetric breast density(VBD) in different ages of Chinese women based on X-ray mammograms.Methods:Based on mammographic images of 1 140 patients from January 2010 to December 2016 in a hospital in Beijing, the VBD of women was assessed by Volpara 1.5.1 and graded according to breast imaging reporting and data system published by American College of Radiology. The patients were divided into two groups according to the median age, and the two independent samples t-test was used to compare them. The patients were also divided into four groups according to age ( <40 years, 40-49 years, 50-59 years, ≥ 60 years), and the breast thickness, breast volume, glandular volume, and VBD were compared using a One-way ANOVA analysis. Results:The median age was 50 years. The compressed breast thickness and breast volume in patients over 50 years were significantly higher than those in patients below 50 years ( t= -8.99, -7.92, P<0.001), while glandular volume and VBD were significantly lower than those below 50 years ( t= 8.11, 18.49, P<0.001). The compressed breast thickness, breast volume, glandular volume, and VBD were statistically significant different among four groups ( F=27.10, 22.34, 25.70, 122.03, P<0.001). Patients over 60 years had the lowest VBD ( t=-12.56, -15.27, -4.57, P<0.001). VBD was negatively correlated with ages ( r=0.47, P<0.001). Conclusions:The compressed breast thickness and breast volume increased with ages, while the glandular volume and VBD decreased with ages.
