The application of the RapidPlan module based on O-ring accelerator in volumetric modulated arc therapy for cervical cancer
10.3760/cma.j.cn112271-20220620-00259
- VernacularTitle:基于环形加速器的RapidPlan模块在宫颈癌容积调强放疗中的研究
- Author:
Zhen ZHOU
1
;
Bo YANG
;
Zhiqun WANG
;
Heling ZHU
;
Xiangyin MENG
;
Tingting DONG
;
Jie QIU
Author Information
1. 中国医学科学院北京协和医院放射治疗科,北京 100730
- Keywords:
O-ring linac;
RapidPlan automatic plan;
Cervical cancer;
Volumetric modulated arc therapy;
Consistency
- From:
Chinese Journal of Radiological Medicine and Protection
2022;42(9):691-696
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinical feasibility and advantages of the RapidPlan module based on Halcyon 2.0 ring medical linear accelerator in the design of volumetric modulated arc therapy (VMAT) plans after cervical cancer surgery.Methods:The data of 98 clinical cervical cancer cases were selected from the database, and VMAT artificial radiotherapy plans were designed based on Halcyon 2.0. Then, the designed plans were imported into the RapidPlan module to train the module for a prediction model with high goodness of fit. Another 20 patients after cervical cancer surgery were selected as the validation set to compare the differences in dosimetry, plan consistency, and plan execution efficiency between the manual plans and RapidPlan automatic plans.Results:The RapidPlan automatic plans could obtain dose distribution of target volume and organs at risk with the same quality as the manual plans. The RapidPlan automatic plans provided slightly inferior protection of the femoral head but superior protection of the spinal cord compared to the manual plans, and the difference was statistically significant ( t = 4.71, P<0.001). The average MU of the RapidPlan automatic plans was 687.46, which was lower than that of the manual plan (815.34), and the difference was statistically significant ( t = 6.09, P < 0.05). The portal dosimetry (PD) verification revealed that the average γ passing rate (1 mm/1%) of the RapidPlan automatic plans was 89.48%and that of the manual plans was 88.22%, and the difference was statistically significant ( t = 3.35, P < 0.05). Conclusion:RapidPlan automatic plans based on the Halcyon 2.0 platform can meet the clinical needs of the VMAT program for cervical cancer and has certain advantages.