Measurement and analysis of 90Y radioactivity in urine of patients treated with 90Y resin microspheres
10.3760/cma.j.cn112271-20220328-00125
- VernacularTitle:90Y树脂微球治疗患者尿液中 90Y放射性活度检测和分析
- Author:
Dexing LIAN
1
;
Shanshan KOU
;
Jianfei LU
;
Jun CHAO
;
Zaiyun ZHU
;
Qingzhao ZHANG
;
Changsong HOU
Author Information
1. 中国疾病预防控制中心辐射防护与核安全医学所 辐射防护与核应急中国疾病预防控制中心重点实验室，北京 100088
- Keywords:
90Y resin microspheres;
Urinary excretion;
Radioactivity
- From:
Chinese Journal of Radiological Medicine and Protection
2022;42(6):460-463
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate 90Y activity concentration in renal excretions during the first 48 hours after being treated with 90Y resin microspheres seleceive internal radiation therapy(SIRI) and to provide advice on the management of patient excreta after surgery. Methods:After surgery, urine excreted from 3 patients during 0-24 h and 24-48 h was collected respectively, and the 90Y activity concentration in urine was tested and analyzed. Results:90Y radioctivity in the urine excreted from 3 patients after surgery was (1 266±258)kBq/GBq during 0-24 h and (140±106) kBq/GBq during 24-48 h, respectively, and 90Y activity concentration were (640±113) kBq/L during 0-24 h and (53±12) kBq/L during 24-48 h. Conclusions:90Y radioactivity in patient′s urine excreted at 1 d was about 10 times higher than that at 2 d. After surgery, patients can accelerate the reduction of free 90Y activity by increasing excretion. Urine excreted by the patients during hospitalization should be handled in accordance with the requirements of the national standard HJ 1188-2021 Radiation protection and safety requirements for nuclear medicine.
