Comparative study of umbilical venous blood flow between congenital heart disease and normal fetus
10.3760/cma.j.cn131148-20220118-00046
- VernacularTitle:先天性心脏病胎儿与正常胎儿脐静脉血流量的对比研究
- Author:
Juan GUO
1
;
Jiancheng HAN
;
Xiaoyan GU
;
Ye ZHANG
;
Xiaowei LIU
;
Lin SUN
;
Ying ZHAO
;
Jian CHEN
;
Xuehao GONG
;
Yihua HE
Author Information
1. 深圳大学第一附属医院 深圳市第二人民医院超声科，深圳 518035
- Keywords:
Ultrasonography, prenatal;
Congenital heart disease;
Fetus;
Umbilical vein, placenta;
The blood flow
- From:
Chinese Journal of Ultrasonography
2022;31(9):774-778
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the differences of umbilical vein diameter(D), time average peak velocity(TAmax) and blood flow between congenital heart disease and normal fetus.Methods:The umbilical vein diameter and time average peak velocity of 69 fetuses with congenital heart disease (disease group) from 22 to 27 weeks were prospectively studied in Maternal-Fetal Medical Center in Fetal Heart Disease of Beijing Anzhen Hospital from May 2021 to September 2021. Q 1 (umbilical venous blood flow) was calculated according to the formular [Q=0.5TAmax·π·(D/2) 2)], and Q 2 (Q 2=Q 1/weight) was calculated according to the fetal weight. At the same time, 111 normal fetuses with matched gestational age were selected as control group. The differences of fetal umbilical vein D, TAmax, Q 1 and Q 2 between the two groups were analyzed. Results:The inner diameter of umbilical vein D, TAmax, Q 1 and Q 2 in the congenital heart disease group were lower than those in the control group(all P<0.05). In the control group, the inner diameter of umbilical vein D, TAmax and Q 1 increased with the increase of gestational age and showed a positive linear correlation( r=0.608, 0.320, 0.626; all P≤0.001), while there was no obvious linear correlation between Q 2 and gestational age( r=0.189, P=0.047). Conclusions:The decrease of umbilical vein D, TAmax, Q 1 and Q 2 in the fetus with congenital heart disease indicates the decrease of effective blood flow in placenta-fetus circulation, which indirectly reflects the decrease of placental function in the fetus with congenital heart disease.
