Pressure-strain loops technique detects the effects of different pacing modes of left bundle branch on left ventricular myocardial work
10.3760/cma.j.cn131148-20220119-00053
- VernacularTitle:压力-应变环评价左束支不同起搏模式对左室心肌做功的影响
- Author:
Peiwei WANG
1
;
Yangxin CHEN
;
Li YANG
;
Shaoxin ZHENG
;
Bingqing DENG
;
Qiong QIU
Author Information
1. 中山大学孙逸仙纪念医院心血管内科,广州 510120
- Keywords:
Echocardiography;
Left bundle branch pacing;
Pressure-strain loops;
Myocardial work;
Mechanical synchrony
- From:
Chinese Journal of Ultrasonography
2022;31(9):753-758
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effects of different pacing modes (unipolar/bipolar) under left bundle branch pacing(LBBP) on ventricular mechanical synchrony and myocardial work using the pressure-strain loop technique.Methods:Twenty-nine patients with LBBP due to symptomatic bradycardia were collected as LBBP group in Sun Yat-sen Memorial Hospital of Sun Yat-sen University from December 2018 to July 2020. Another 29 matched patients with right ventricular pacing (RVP) during the same period were also included as a RVP group. Each LBBP patient was programmed to different pacing modes (uni-/bio-polar) within 1 week after the operation.Under each pacing mode, the inter- and intra-ventricular mechanical synchronization were evaluated. Meanwhile, the global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE) were obtained by the left ventricular pressure-strain loops technique.Results:Compared with the RVP group, the mechanical synchrony in the LBBP group was significantly improved (all P<0.05). GWI, GCW, and GWE increased, while GWW decreased, and the differences were statistically significant (all P<0.05), there were no significant differences in ventricular mechanical synchronization, GWI, GCW, GWE, and GWW between unipolar and bipolar pacing in the LBBP group (all P>0.05), there were no significant differences in these parameters when increasing output voltage (all P>0.05). Conclusions:LBBP induces better mechanical synchronization and higher myocardial work efficiency than RVP. Different LBBP pacing modes do not affect ventricular mechanical synchronization and myocardial work efficiency.