Value of contrast-enhanced ultrasound liver imaging reporting and data system version 2017 and MRI liver imaging reporting and data system version 2018 in predicting the malignant risk of focal liver lesion
10.3760/cma.j.cn131148-20220131-00083
- VernacularTitle:超声造影LI－RADS 2017版与MRI LI－RADS 2018版对肝内局灶性病变恶性风险的预测价值
- Author:
Lili ZHENG
1
;
Xinping REN
;
Ruokun LI
;
Weiwei ZHAN
;
Weixia LI
Author Information
1. 无锡市新吴区新瑞医院（上海交通大学医学院附属瑞金医院无锡分院）超声科，无锡 214028
- Keywords:
Contrast-enhanced ultrasound;
Magnetic resonance imaging;
Liver Imaging Reporting and Data System;
Hepatocellular carcinoma;
Focal liver lesion
- From:
Chinese Journal of Ultrasonography
2022;31(8):671-677
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the predictive value of contrast-enhanced ultrasound(CEUS) Liver Imaging Reporting and Date System(LI-RADS) version 2017 with magnetic resonance imaging(MRI) LI-RADS version 2018 applied alone or in combination for focal liver lesions in high-risk patients.Methods:From January 2018 to October 2021, the clinical and imaging datas of 212 patients with 300 nodules underwent CEUS and contrast-enhanced MRI(CEMRI) within 4 weeks in Ruijin Hospital and its Wuxi branch were retrospectively analyzed. Each nodule was categorized according to the CEUS LI-RADS v2017 and CT/MRI LI-RADS v2018. Inter-modalities agreement was assessed with Cohen′s Kappa. The diagnostic performances of the two classification criteria applied alone and in combination for the predictive value of malignant risk of focal liver lesions were compared using histopathology or follow-up as gold standard.Results:The inter-modalities agreement of CEUS LI-RADS v2017 and MRI LI-RADS v2018 was moderate (Kappa=0.441). The specificity of CEUS LR-5, MRI LR-5 and CEUS LR-5+ MRI LR-5 in the diagnosis of HCC was 93.66%, 95.07% and 88.73% ( P>0.05), respectively, positive predictive values of them were 93.13%, 93.81% and 89.81%( P>0.05), respectively. The sensitivity of CEUS LR-M, MRI LR-M and CEUS LR-M+ MRI LR-M in the diagnosis of non-HCC malignancy was 85.71%, 82.86% and 100%, respectively. CEUS LR-M+ MRI LR-M had higher sensitivity than MRI LR-M( P=0.033), whereas no difference was found between CEUS LR-M+ MRI LR-M and CEUS LR-M( P=0.063). Conclusions:The inter-modalities agreement of the LI-RADS category between CEUS and MRI is moderate. The specificity and positive predictive values of HCC in LR-5 of the CEUS and MRI LI-RADS are comparable. In addition, the sensitivity of non-HCC malignancy in LR-M of the CEUS and MRI LI-RADS are comparable. The combined application of CEUS and MRI LR-M can improve the diagnostic sensitivity of non-HCC malignancy.
