Alteration of right ventricular function after catheter ablation in patients with persistent atrial fibrillation and concomitant heart failure with preserved ejection fraction
10.3760/cma.j.cn131148-20211103-00804
- VernacularTitle:持续性心房颤动合并射血分数保留的心力衰竭患者射频消融术后右心室收缩功能的改变
- Author:
Yan SHEN
1
;
Di XU
;
Minglong CHEN
;
Xichen LIANG
;
Xiaoxian WANG
;
Beibei GE
;
Yanjuan ZHANG
;
Jing YAO
Author Information
1. 南京医科大学第一附属医院心内科，南京 210029
- Keywords:
Persistent atrial fibrillation;
Ventricular function, right;
Catheter ablation
- From:
Chinese Journal of Ultrasonography
2022;31(6):490-496
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the alteration of right ventricular function after catheter ablation in patients with persistent atrial fibrillation(PAF) and concomitant heart failure with preserved ejection fraction (HFpEF).Methods:The prospective observational study was performed in patients with HFpEF-PAF and undergoing first-time radiofrequency ablation procedures in the First Affiliated Hospital of Nanjing University between May to December 2019. Right ventricular functional parameters were measured before and 5 days, 1, 3, 6 and 12 months after the ablation by transthoracic echocardiography, respectively, including the right ventricular fractional area change (RVFAC), tricuspid annular plane systolic excursion(TAPSE), tricuspid annular diameter (TVAD), tricuspid annular peak systolic speed(TDI-S′) and longitudinal strain of right ventricular free wall (RVFLS). Meanwhile, routine ECG and Holter recordings were performed at each follow-up time point.Results:In this study, atrial fibrillation (AF) recurrence occurred in 4 patients at the 3rd month after ablation, and 7 patients failed to follow up due to the Covid-19. Finally, 19 patients were followed up for the evaluation of cardiac function after catheter ablation. Compared with pre-ablation, right ventricular structural and functional paramters(RVFAC, TAPSE, TVAD, TDI-S′, RVFLS) improved significantly at all stages of follow-up( all P<0.05). Patients with atrial fibrillation recurrence had lower RVFLS and TDI-S′ at the baseline( P=0.039, P=0.019). Conclusions:Right ventricular function could improve in HFpEF-PAF patients who maintain sinus rhythm after radiofrequency ablation.
