A case of high level of elevated antiphospholipid antibodies positive secondary to infective endocarditis
10.3760/cma.j.cn101721-20220408-000112
- VernacularTitle:感染性心内膜炎继发高滴度抗磷脂抗体阳性1例
- Author:
Linguang LI
1
;
Min XIAO
;
Song CAI
Author Information
1. 北京市隆福医院心血管内科，北京 100010
- Keywords:
Infective endocarditis;
Antiphospholipid antibodies;
Thrombosis
- From:
Clinical Medicine of China
2022;38(4):366-368
- CountryChina
- Language:Chinese
-
Abstract:
It is quiet rare that transient high level of elevated antiphospholipid (aLP) antibodies are triggered by infective endocarditis(IE). We report a young woman who went to hospital because of fever was diagnosed with IE, she was suffering from lower and upper arterial thrombosis, tests showed that anticardiolipin and anti-beta2-glycoprotein(GP)-1 IgM antibodies elevated highly. She had mitral valve replacement surgery, echocardiography detected vegetation on mitral valve, multiple blood culture showed negative, after treatment of antibiotics,the second cardiac surgery and warfarin, the patient got stable condition and the upper limb arterial thrombosis disappeared. Three months later, aLP antibodies tests came back negative. This case illustrate that IE could lead to transient high level of elevated aLP antibodies, does that increase the risk of thrombosis of IE patient is unknown, what if we find that phenomenon earlier and prescribe anticoagulant drugs, that need more observation.
