The incidence of malignant tumors and its risk factors in patients on maintenance hemodialysis
10.3760/cma.j.cn431274-20220418-00346
- VernacularTitle:维持性血液透析患者恶性肿瘤发生率及危险因素分析
- Author:
Jiaqi XU
1
;
Yumin LI
;
Bixian ZHONG
;
Shaohua LIU
;
Ying LEI
;
Yunfang ZHANG
;
Yanyan SU
Author Information
1. 南方医科大学附属花都医院（广州市花都区人民医院）肾病学科，广州 510800
- Keywords:
Hemodialysis;
Neoplasms;
Risk factors
- From:
Journal of Chinese Physician
2022;24(11):1661-1664
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the incidence of malignant tumors and its risk factors in patients on maintenance hemodialysis.Methods:Clinical data of 627 hemodialysis patients in Huadu District People′s Hospital of Guangzhou who met the inclusion criteria and exclusion criteria from January 2015 to December 2020 were retrospectively collected. Clinical characteristic of patients with malignant tumors was summarized. Multivariate logistics regression analysis was performed to explore the related factors of malignant tumors.Results:Among the 627 patients, 19(3.03%) developed malignant tumors. There were 14 males and 5 females with a mean age of (65.7±13.7)years. Their mean dialysis duration was (45.16±38.18)months. Gastrointestinal tumor was the most common tumor type (9/19). Univariate analysis showed that the age of the patients combined with malignant tumors was significantly higher, and the serum prealbumin was significantly lower than those patients without malignant tumors (all P<0.05). Logistic regression analysis showed that age was the independent risk factor of developing cancers after adjusting dialysis age, hemoglobin, albumin and parathyroid hormone ( P<0.05). Conclusions:The incidence of malignant tumor is significantly higher in maintenance hemodialysis patients than that in the general population. Age is the risk independent risk factor. Therefore, we should strengthen the monitoring of elderly hemodialysis patients, discover the disease in time, and take measures to improve the prognosis.
