The immune modulation of Th17 and its related cytokines in inflammatory bowel diseases

VernacularTitle:Th17及其相关细胞因子在炎症性肠病中的免疫调控作用
Author: Chao WU ¹ ; Hairong ZHANG ; Wei YU ; Yuan XUE ; Yibo WANG ; Guangxi ZHOU
Author Information

1. 济宁医学院临床医学院，济宁　272067
Keywords: Inflammatory bowel diseases; Th17 cells; Interleukin-17; Immune regulation
From: Journal of Chinese Physician 2022;24(8):1270-1273
CountryChina
Language:Chinese
Abstract: Inflammatory bowel diseases (IBD) are a kind of non-specific inflammatory disease that occurs in gastrointestinal tract. Abnormal immune regulation is a key factor in its pathogenesis. The acquired immune regulation is mediated by helper T cells (Th), which is reported to play an important role in the pathogenesis of IBD. Th17 is a subtype of CD4 + T cells that could specifically produce interleukin-17 (IL-17) and other related cytokines. In this paper, we review the immune modulation of Th17 and its related cytokines in IBD.