Application of psychotherapy in treatment-resistant depression
10.3760/cma.j.cn371468-20220405-00161
- VernacularTitle:心理治疗在难治性抑郁中的应用
- Author:
Jiayu YAO
1
;
Jianyin QIU
Author Information
1. 上海交通大学医学院附属精神卫生中心心理咨询科，上海 200030
- Keywords:
Psychotherapy;
Treatment-resistant depression;
Intervention effect;
Therapeutic mechanism
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2022;31(11):1046-1051
- CountryChina
- Language:Chinese
-
Abstract:
Treatment-resistant depression (TRD) is characterized by a high suicide rate and a high recurrence rate. The effect of the medicine on TRD is not ideal with obvious side effects. Psychotherapy is an important method recommended in many guidelines for the treatment of depression. However, previous studies and clinical applications have paid little attention to the application of psychotherapy in TRD. Therefore, based on recent studies, this paper reviews the effects of psychotherapy on the depressive symptoms, suicide risk, and recurrence risk in TRD. Further, the possible therapeutic mechanisms are discussed, including the improvement of interpersonal function by dealing with early trauma in TRD, therefore alleviating symptoms; intervening in the dysfunctional cognitive pattern of TRD to help them cope with negative life events, therefore reducing stress and depression. Combined with the limitations of existing studies, the following directions can be considered in the future: improving the research quality, measuring behavioral and physiological indicators to further clarify the therapeutic mechanism, identifying ways in which psychotherapy can be combined with other treatments, exploring the group and online therapy to increase accessibility of psychotherapy for TRD.
