Research progress of light therapy for mood disorders
10.3760/cma.j.cn371468-20220128-00041
- VernacularTitle:光照治疗情绪相关疾病的研究进展
- Author:
Ruojia REN
1
;
Li YANG
;
Xueyi WANG
Author Information
1. 河北医科大学第一医院精神卫生中心，石家庄 050031
- Keywords:
Light therapy;
Depression;
Bipolar disorder;
Intrinsically photosensitive retinal ganglion cells;
Neural circuit;
Circadian rhythm
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2022;31(7):664-670
- CountryChina
- Language:Chinese
-
Abstract:
Light therapy, a non-intrusive approach, is now considered as a promising new treatment method for a variety of mood disorders such as depression, bipolar disorder, postpartum depression and so on. However, the neural mechanism of light therapy to regulate emotions is still unclear, and the clinical application of light therapy and its side effects are still controversial. Light therapy regulates mood may be related to the changes of neural circuit mediated by intrinsically photosensitive retinal ganglion cells(ipRGCs), clock gene expression, circadian rhythm and sleep structure. In this paper, the treatment of mood disorders by light has been discussed, and a variety of neural circuits and molecular biological mechanisms of light therapy are introduced, meanwhile, the current situation and side effects of light therapy have been analyzed, in order to provide evidence for the application and promotion of light therapy in the treatment of mood disorders.
