Volume dynamics and volume management in intensive care unit patients

VernacularTitle:容积动力学与ICU患者容量管理
Author: Yingzhi QIN ¹ ; Yuning HE ; Quansheng FENG ; Zhibo LI ; Zhiyong WANG ; Yaxuan WU ; Jing ZHAO ; Xinjing GAO
Author Information

1. 天津市第三中心医院重症医学科，天津　300170
Keywords: Volume dynamics; Two-compartment model; Plasma volume; Interstitial fluid space; Crystalloid fluid
From: Chinese Critical Care Medicine 2022;34(7):673-675
CountryChina
Language:Chinese
Abstract: Volume dynamics is a two-compartment dynamical model using hemoglobin (Hb) derived plasma diluted level as input data and urine output as input variable through consecutive repeated measurements of Hb concentration in the blood during infusion. It could be applied to evaluate and guide crystalloid fluid rehydration for patients with dehydration or hypovolemia and during anesthesia or surgery. Volume dynamics could be also used to quantificate of strains, hypovolume, and the change of fluid distribution and elimination caused by anesthesia or surgery. The factors which influence the volume resuscitation are complex, including gender, age, hemodynamic state [mean arterial pressure (MAP)], health and stress state, renal function, consciousness, surgical or anesthesia state and so on, which may affect the half-life, distribution, and volume of the fluid. This article summarizes and analyzes the pathophysiological changes of crystalloids fluid in vivo, in order to provide reference for volume management in critically ill patients.