A case of improved Menetrier's disease after the eradication of Helicobacter pylori and treatment with a proton pump inhibitor.
- Author:
Ji Hoon YOON
1
;
Seung Jei PARK
;
Jae Won CHOI
;
Sung Won CHOI
;
Seung Keun PARK
;
Hee Ug PARK
;
Hye Sook KIM
Author Information
1. Department of Internal Medicine, Maryknoll Hospital, Busan, Korea. bigjohn72@hanmail.net
- Publication Type:Case Report
- Keywords:
Menetrier's disease;
Helicobacter pylori
- MeSH:
Adult;
Body Weight;
Dyspepsia;
Gastritis;
Gastritis, Hypertrophic;
Gastroscopy;
Helicobacter;
Helicobacter pylori;
Humans;
Hyperplasia;
Mucous Membrane;
Proton Pumps;
Protons
- From:Korean Journal of Medicine
2010;78(6):737-740
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Menetrier's disease is a protein-losing hypertrophic gastropathy characterized by diffuse tremendous thickening of the gastric wall caused by excessive proliferation of the mucosa. Although the cause of Menetrier's disease is unknown, an association with Helicobacter pylori has been reported. A 42-year-old man was hospitalized for the evaluation of progressive body weight loss and indigestion for 6 months, with recently aggravated epigastric discomfort. Gastroscopy revealed prominent mucosal folds in the body and fundus. The histological findings revealed gastritis with erosions and foveolar hyperplasia. After eradicating the Helicobacter pylori and treatment with a proton pump inhibitor, clinical and endoscopic resolution ensued.
