Application of Global Leadership Initiative on Malnutrition criteria in the diagnosis of malnutrition in gastric cancer patients
10.3760/cma.j.cn115822-20220725-00143
- VernacularTitle:GLIM标准下胃癌患者营养不良诊断的应用研究
- Author:
Lili DING
1
;
Liru CHEN
;
Bo CHENG
;
Lijuan WANG
;
Chengyu LIU
;
Mingwei ZHU
Author Information
1. 北京医院临床营养科，国家老年医学中心 中国医学科学院老年医学研究院100730
- Keywords:
GLIM criteria;
Gastric cancer;
Malnutrition;
Cancer patients
- From:
Chinese Journal of Clinical Nutrition
2022;30(5):294-299
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrospectively investigate the incidence of malnutrition in patients with gastric cancer in China, and to explore the applicability of Global Leadership Initiative on Malnutrition (GLIM) diagnostic criteria.Methods:Data were extracted from National Multi-center Investigation and Study on Dynamic Changes of Nutritional Status of Inpatients database led by Geriatric Nutrition Support Group of the Chinese Society of Parenteral and Enteral Nutrition. A retrospective analysis in patients with gastric cancer was conducted. Involuntary weight loss, low body mass index (BMI) and muscle mass loss were adopted as phenotypic indicators in GLIM criteria for malnutrition diagnosis and the application of GLIM criteria for malnutrition diagnosis in patients with gastric cancer was evaluated.Results:In a total of 563 gastric cancer patients, 203 cases were diagnosed with malnutrition per GLIM criteria and 193 cases without malnutrition were identified as control using 1:1 propensity score matching. There were significant differences in body weight, BMI, right calf circumference, right hand grip strength, total cholesterol, hemoglobin, albumin and total protein between malnutrition group and non-malnutrition group ( P < 0.05). After muscle mass loss was removed from the phenotype indicators in GLIM criteria, the hospitalization duration in patients with malnutrition was (16.15±7.04) days compared with (14.28±6.70) days in patients without malnutrition, demonstrating statistically significant difference ( χ2= 0.442, P = 0.007). Conclusions:Gastric cancer patients showed high incidence of malnutrition. The cut-off value of calf circumference reported in foreign populations may be unsuitable to apply in Chinese population. Further clinical researches are needed to determine the optimal cut-off calf circumference value for Chinese individuals.
