Meta-analysis of the efficacy and safety of percutaneous gastrostomy in stroke patients
10.3760/cma.j.cn115822-20210902-00174
- VernacularTitle:经皮胃造瘘术在脑卒中患者中应用有效性与安全性的Meta分析
- Author:
Haiyan WANG
1
;
Hong LI
;
Nannan HU
;
Shaohua GONG
;
Jie ZHANG
Author Information
1. 北京医院 老年医学病房 国家老年医学中心 中国医学科学院老年医学研究院100730
- Keywords:
Percutaneous gastrostomy;
Stroke;
Efficacy;
Safety;
Systematic review
- From:
Chinese Journal of Clinical Nutrition
2022;30(2):114-122
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the efficacy and safety of enteral nutrition via percutaneous endoscopic gastrostomy (PEG) and nasogastric feeding (NGF) in stroke patients.Methods:Databases including PubMed, EMbase, Cochrane Library, Wangfang database (Wangfang data), CNKI and CBM were searched for relevant literature about enteral nutrition via percutaneous gastrostomy in stroke patients. Literature screening, data extraction and quality evaluation of the included study were performed by two independent investigators. RevMan5.3 was used for data analysis.Results:A total of 12 publications were included, of which 7 were randomized controlled trials (RCTs) and 5 were non-RCTs. There were no significant differences in BMI, hemoglobin, serum albumin and mortality. In terms of safety, PEG resulted in effective decreases in the incidence of pneumonia (RR=0.31, 95% CI: 0.18-0.53, P<0.01), hypoproteinemia (RR=0.34, 95% CI: 0.17-0.68, P=0.003) and fluid and electrolyte disorder (RR=0.24, 95% CI: 0.06-0.92, P=0.04) compared with NGF while there was no significant difference in the incidence of abdominal distension, diarrhea and gastrointestinal bleeding .Conclusion:Compared with NGF, enteral nutrition with PEG can effectively reduce the incidence of pneumonia and the risk of infections in stroke patients and can also reduce the incidence of hypoproteinemia and fluid and electrolyte disorder, leading to improved patient outcomes.
