A Case of Angiocentric T-cell Lymphoma.
- Author:
Sang Won JEONG
1
;
Sang Won LEE
;
Nyung Hoon YOON
;
Seung Hoon CHA
;
Seok Don PARK
Author Information
1. Department of Dermatology, Wonkwang University School of Medicine, Iksan, korea.
- Publication Type:Case Report
- Keywords:
Angiocentric T-cell lymphoma;
Epstein-Barr virus
- MeSH:
Adult;
Drug Therapy;
Elbow;
Female;
Herpesvirus 4, Human;
Humans;
Lymphocytes;
Lymphoma, T-Cell*;
Nasal Cavity;
Ovum;
Polymerase Chain Reaction;
Sepsis;
Skin;
T-Lymphocytes*
- From:Korean Journal of Dermatology
2000;38(2):240-244
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 40-year-old female patient, known angiocenteric T-cell lymphoma on nasal cavity, was transfered from the department of hemato-oncology for the evaluation of egg sized pinkish-yellow indurated mass with central necrotic tissue on the left medial elbow. Histopathologic findings revealed angiocentric, angioinvasive, and angiodestructive infiltrate containing atypical lymphocytes. The infiltrative cells were positivly stained with antibody to CD45RO, LCA, but not with antibody CD20. The atypical infiltrated perivascular lymphoid cells were positive to Epstein-Barr virus in situ polymerase chain reaction. She was treated with combined chemotherapy and radiation therapy, but she died due to sepsis. We herein report a rare case of angiocentric T-cell lymphoma on the nasal cavity and skin associated with Epstein-Barr virus.
