A Case of Necrobiosis Lipoidica Diabeticorum with Koebner Phenomenon.
- Author:
Dong Kyu HWANG
1
;
Jong Min PARK
;
Sang Jin KWON
;
Hee Joon YU
;
Yong Wook PARK
Author Information
1. Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Necrobiosis lipoidica diabeticorum;
Koebner phenomenon
- MeSH:
Adrenal Cortex Hormones;
Biopsy;
Collagen;
Culicidae;
Elastic Tissue;
Epithelioid Cells;
Female;
Forearm;
Giant Cells;
Granuloma;
Histiocytes;
Humans;
Injections, Intralesional;
Middle Aged;
Mucins;
Necrobiosis Lipoidica*;
Necrobiotic Disorders*;
Psoriasis;
Recurrence;
Skin Manifestations;
Triamcinolone Acetonide
- From:Korean Journal of Dermatology
2000;38(2):245-248
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The isomorphic response of Koebner is a well-known phenomenon commonly associated with psoriasis, but it has been also described in conjuction with a host of other disorders. However it has seldom been associated with necrobiosis lipoidica diabeticorum, a rare skin manifestation of diabetes mellicuts. In this report, we describe a 59-year-old woman who developed necrobiosis lipoidica diabeticorum on the left shin where a mosquito had bitten her 2 months ago. Four months ago, she was diagnosed as necrobiosis lipoidica diabeticorum on the right forearm and shin by biopsy and the lesions were improved with corticosteroids intralesional injection. The lesions were asymptomatic and had grown slowly. Histopathological findings showed a large palisading granulomas composed of histiocytes, epithelioid cells and areas of necrobiosis of collagen with multinucleated giant cells. Van Gieson stain showed decreased and fragmented elastic fibers and there were no deposits of mucin in the necrobiotic areas. The lesions were improved with triamcinolone acetonide intralesional injection and there was no recurrence during 4 months.
