A Case of Cutaneous Metastatic Ewing's Sarcoma.
- Author:
Jeong Hyun SHIN
1
;
So Yun CHO
;
Kyu Kwang WHANG
;
Jeong Hee HAHM
Author Information
1. Department of Dermatology, College of Medicine, Ewha Womans University Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Ewing's sarcoma;
CD99;
Neuroectodermal origin;
Cutaneous metastasis
- MeSH:
Drug Therapy;
Female;
Humans;
Membranes;
Neoplasm Metastasis;
Neural Plate;
Pelvic Bones;
Prognosis;
Sarcoma, Ewing*;
Skin;
Young Adult
- From:Korean Journal of Dermatology
2000;38(2):249-253
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Ewing's sarcoma is a highly anaplastic, small round cell tumor, primarily arising in the intramedullary portion of the bone, and metastasis is common. Its origin is unknown. We describe a case of cutaneous metastatic Ewing's sarcoma in the pubic area in a 23-year-old female, who had been diagnosed as having Ewing's sarcoma of the pelvic bone three years ago, and treated by wide excision, chemotherapy and radiation therapy. Histopathologic examination of her nodular lesion revealed a tumor of small round cells whose membranes were positive for CD99. She was managed by conservative treatment but expired one month later. To our knowledge, Ewing's sarcoma metastatic to the skin has not been reported previously in the world. This case supports the neuroectodermal origin of this tumor and that cutaneous metastasis of this tumor is a hallmark of grave prognosis.
