Clinical study of Xuefu Zhuyu Capsule combined with drilling and drainage in the treatment of chronic subdural hematoma
10.3760/cma.j.cn115455-20220518-00455
- VernacularTitle:血府逐瘀胶囊联合钻孔引流术治疗慢性硬膜下血肿的临床研究
- Author:
Wei WEI
1
;
Dianshi JIN
;
Xin CHEN
;
Junmin TAO
Author Information
1. 大连市中心医院神经外二科，大连 116033
- Keywords:
Hematoma, subdural, chronic;
Xuefu Zhuyu Capsule;
Burr-hole craniotomy;
Effectiveness
- From:
Chinese Journal of Postgraduates of Medicine
2022;45(10):868-872
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify the effects of Xuefu Zhuyu Capsule (XZC) on the surgical treatment of patients with chronic subdural hematoma (CSDH).Methods:Retrospectively collected 96 pairs of patients who undergoing burr-hole craniotomy (BHC) for CSDH from January 2016 to December 2019 in Dalian Municipal Central Hospital. Clinical characteristics and imaging information of each patient were extracted, the follow-up period was six months. Differences in demographics and postoperative outcomes were compared between BHC+XZC group and BHC only group. Univariate analysis and multivariate analysis with Logistic regression model were performed to determine independent associations among the various probable effective factor. The relationship between related factors and effectiveness of CSDH was estimated with odds ratio ( OR) and 95% CI. Results:Effectiveness in 87 cases (90.6%) patients with surgery and received XZC postoperatively was significantly higher than 76 cases (79.2%) patients who underwent surgery alone. Multivariate Logistic regression analysis showed postoperative administration of XZC and preoperative Glasgow coma scale (GCS) score were independent protective factors for CSDH to improve therapeutic effect.Conclusions:This study suggested postoperative administration of XZC for CSDH patients can improve the therapeutic effect, a higher preoperative GCS score is contributed to the postoperative effect.
