Clinical staging and prognostic risk factors for ocular adnexal lymphoma
10.3760/cma.j.cn115989-20211231-00727
- VernacularTitle:眼附属器淋巴瘤临床分期和预后危险因素评估
- Author:
Tianming JIAN
1
;
Fei GAO
;
Wanchen YANG
;
Dongrun TANG
;
Yanjin HE
;
Fengyuan SUN
Author Information
1. 天津医科大学眼科医院 天津医科大学眼视光学院 天津医科大学眼科研究所 国家眼耳鼻喉疾病临床医学研究中心天津市分中心 天津市视网膜功能与疾病重点实验室，天津 300384
- Keywords:
Lymphoma;
Prognosis;
Survival analysis;
Ocular adnexa;
Risk factors;
TNM classification;
Ann Arbor classification
- From:
Chinese Journal of Experimental Ophthalmology
2022;40(8):743-751
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the influence of the clinical staging and different risk factors for the prognosis of ocular adnexal lymphoma.Methods:An ambispective cohort study was conducted.Seventy-four patients diagnosed with primary ocular adnexal lymphoma by pathology at Tianjin Medical University Eye Hospital from November 2010 to December 2018 were enrolled.TNM staging was performed according to local tumor extent, lymph node or systemic involvement.Ann Arbor staging was carried out according to lymph node involvement and extranodal extension.The pathological subtype was classified according to World Health Organization classification of lymphoma.The outcome of disease progression or death was analyzed.Kaplan-Meier method was used for univariate survival analysis.Cox proportional hazard model was employed for multivariate survival analysis to predict the risk factors affecting prognosis, hazard ratio ( HR) and 95% confidence interval ( CI) were estimated.This study adhered to the Declaration of Helsinki.The study protocol was approved by an Ethics Committee of Tianjin Medical University Eye Hospital (No.2021KY[L]-32). Written informed consent was obtained from all patients before entering the cohort. Results:For TNM staging, there were 68 cases in stage
