Neuroprotection and neuroregeneration treatment strategy in non-arteritic anterior ischemic optic neuropathy
10.3760/cma.j.cn115989-20190615-00261
- VernacularTitle:非动脉炎性前部缺血性视神经病变的神经保护及神经再生治疗策略
- Author:
Yuyu CHOU
1
;
Jin MA
;
Yong ZHONG
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院眼科，北京 100730
- Keywords:
Optic neuropathy;
Ischemic/therapy;
Neuroprotection;
Nerve regeneration
- From:
Chinese Journal of Experimental Ophthalmology
2022;40(7):675-679
- CountryChina
- Language:Chinese
-
Abstract:
Non-arteritic anterior ischemic optic neuropathy (NAION) is a disease characterized by acute, painless visual acuity loss and visual field impairment, and there is still lack of unified and effective treatment.As new therapeutic strategies, neuroprotection and nerve regeneration have aroused wide public concern, which aim to prevent degeneration and death of neurons or establish a new neural circuit through inhibiting apoptosis pathway and inflammation, promoting axon growth and applying stem cells.Plenty of studies have applied the strategies to NAION patients or NAION animal models, which achieved certain success, but the limitations exist at the same time.For the sake of exploring practical therapies of NAION, researches on the neuroprotection and nerve regeneration strategies of NAION in recent years were reviewed in this article.
