Comparison of the predictive value of vasoactive-inotropic score, shock score and lactate level for the outcome of septic shock in term infants
10.3760/cma.j.issn.2096-2932.2022.06.003
- VernacularTitle:血管活性药物评分、休克评分和乳酸水平对脓毒性休克足月儿结局的预测价值
- Author:
Yingyi LIN
1
;
Dongju MA
;
Jing ZHANG
;
Jing MO
;
Junjuan ZHONG
;
Chun SHUAI
;
Yue WANG
;
Xiuzhen YE
Author Information
1. 广东省妇幼保健院新生儿科，广州 510000
- Keywords:
Vasoactive-inotropic score;
Term infant;
Septic shock;
Outcome;
Prognosis
- From:Chinese Journal of Neonatology
2022;37(6):494-498
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the predictive value of vasoactive-inotropic score (VIS), shock score and lactate level for the outcome of term infants with septic shock.Methods:From January 2019 to October 2020, clinical data of term infants with septic shock admitted to our department were reviewed. According to their clinical outcome, the infants were assigned into the survival group and the deceased group and the differences of the two groups were compared. Logistic regression was used to determine the risk factors of mortality in term infants with septic shock. Receiver operating characteristic curve was used to compare the predictive efficacy of VIS, shock score and lactate level for the outcome of septic shock.Results:Significant differences existed between the survival group and the deceased group in the following: maximum VIS, maximum shock score, maximum lactate level, the mean value of VIS during the second 24 h, the mean value of lactate during the first and second 24 h ( P < 0.05). Meanwhile, maximum VIS ( OR = 1.038, 95% CI 1.014~1.063), maximum shock score ( OR = 2.372, 95% CI 1.126~4.999) and the mean value of lactate during the first 24h ( OR = 2.983, 95% CI 1.132~7.862) were correlated with mortality in the infants ( P < 0.05). The area under the curve of maximum VIS was the most prominent, with 58.5 as cut-off. Conclusions:Among the three indicators, VIS has the best predictive value for mortality outcome in term infants with septic shock, followed by shock score and lactate level.
