Research progress of the FLOT regimen in neoadjuvant treatment for gastric cancer
10.3760/cma.j.cn115610-20220422-00226
- VernacularTitle:FLOT方案在胃癌新辅助治疗中的研究进展
- Author:
Tao WANG
1
;
Keshen WANG
;
Huinian ZHOU
;
Zeyuan YU
;
Zuoyi JIAO
Author Information
1. 兰州大学第二医院普通外科，兰州 730030
- Keywords:
Stomach neoplasms;
Tumor therapy;
Neoadjuvant chemotherapy;
Peri-operative treatment;
FLOT
- From:
Chinese Journal of Digestive Surgery
2022;21(6):822-826
- CountryChina
- Language:Chinese
-
Abstract:
With the deepening research of comprehensive treatment for gastric cancer, the FLOT regimen has begun to be used for the treatment of gastric cancer patients. FLOT neoadjuvant regimen can significantly improve the R 0 resection rate and prolong the overall survival time of locally advanced gastric cancer patients. FLOT regimen combined with immune-checkpoint inhibi-tors, targeted therapy and hyperthermic intraperitoneal chemotherapy have great potential in neo-adjuvant therapy for gastric cancer. The authors systematically analyse the development history and latest clinical research progress of FLOT neoadjuvant regimen for gastric cancer based on their clinical practice experience.
