Transfusion-related acute lung injury
10.3760/cma.j.issn.1673-4912.2022.08.005
- VernacularTitle:输血相关急性肺损伤
- Author:
Zheng LI
1
;
Lidan CUI
Author Information
1. 国家儿童医学中心 首都医科大学附属北京儿童医院重症医学科 100045
- Keywords:
Transfusion-related acute lung injury;
Acute respiratory distress syndrome
- From:
Chinese Pediatric Emergency Medicine
2022;29(8):595-599
- CountryChina
- Language:Chinese
-
Abstract:
Transfusion-related acute lung injury (TRALI) is an acute and fatal complication of blood product transfusion.TRALI is a syndrome, which diagnosed by the basis of clinical signs.The pathogenesis of TRALI is unclear and the hypothesis of two-hit model is generally accepted.At present, there is no specific treatment for TRALI.Treatment of the patient with TRALI is mainly supportive.The rational transfusions can avoid the occurrence of TRALI.The incidence of TRALI has been decreased by making the mainly measure of avoiding transfusions of plasma from multiparous female donors.