The effects of Mediterranean diet on cardiovascular risk factors in patients with type 2 diabetes: a Meta-analysis
10.3760/cma.j.cn211501-20220228-00570
- VernacularTitle:地中海饮食对2型糖尿病患者心血管危险因素影响的Meta分析
- Author:
Xing ZHENG
1
;
Wenwen ZHANG
;
Xiaojuan WAN
;
Xiaoyan LYU
;
Peng LIN
;
Aijun WANG
;
Shucheng SI
;
Fuzhong XUE
;
Yingjuan CAO
Author Information
1. 山东大学齐鲁医院肿瘤内科，济南 250012
- Keywords:
Meta-analysis;
Type 2 diabetes;
Mediterranean diet;
Cardiovascular risk
- From:
Chinese Journal of Practical Nursing
2022;38(18):1434-1441
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of Mediterranean diet on blood glucose control and cardiovascular risk factors in patients with type 2 diabetes.Methods:As to December 2021, the PubMed, Cochrance Central Register of Controlled Trials and Cochrance Database, Cochranc Library, Embase, China National Knowledge Infrastructure and Wanfang Medical Network system were searched for clinical randomized controlled trials(RCTs) of Mediterranean diet in patients with type 2 diabetes to conduct Meta-analysis The main observation index were cardiovascular risk factors, and the mean difference and its 95% confidence interval were used to estimate the effect size.Results:There were six RCTs, and 1181 patients met the inclusion criteria and entered the Meta-analysis. Compared with the control group, the intervention group can significantly reduce the level of systolic blood pressure ( MD=-1.20, 95% CI-2.21 to -0.19) and diastolic blood pressure ( MD=-4.17, 95% CI-7.12 to -1.22) in patients with type 2 diabetes mellitus, but there were no significant difference in the level of TC ( MD=2.92, 95% CI-0.84 to-6.67), HDL ( MD=2.33, 95% CI-0.27 to -4.92) and LDL ( MD=-2.34, 95% CI-5.67 to -0.99) between the two groups (all P>0.05). Conclusions:The meta-analysis provided evidence the Mediterranean diet showed the beneficial improvements in blood pressure glycemic control, but the effect of Mediterranean diet on lipid profile was not significant, which needed further verification.
