Efficacy of non-pharmaceutical interventions for chemotherapy-induced nausea and vomiting:an overview of systematic reviews
10.3760/cma.j.cn211501-20210727-02126
- VernacularTitle:非药物干预治疗化疗相关性恶心呕吐有效性的系统评价再评价
- Author:
Xin ZHANG
1
;
Lichun XU
;
Liyu LIN
;
Yuxin HUANG
;
Panpan ZHUANG
Author Information
1. 福建中医药大学护理学院，福州 350122
- Keywords:
Nausea;
Vomiting;
Chemotherapy;
Non-pharmacological interventions;
Overview of systematic reviews
- From:
Chinese Journal of Practical Nursing
2022;38(17):1348-1355
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To re-evaluate the quality of methodology and outcome indicators for systematic reviews/meta-analysis about the effectiveness of non-pharmacological interventions for chemotherapy-related nausea and vomiting(CINV).Methods:The Cochrane Library, PubMed, Embase, Web of Science, CNKI, Wanfang, VIP and CBM for systematic reviews/meta-analysis on the effectiveness of non-pharmaceutical intervention in the prevention or treatment of CINV from inception to May 2021 were searched. The methodological quality of the included literature was evaluated by the AMSTAR 2 quality evaluation tool, and the quality of the evidence for the outcome indicators was evaluated by GRADE system.Results:A total of 24 articles were included, 7 of the AMSTAR 2 quality evaluation results were low-level, and the remaining 17 were all very low-level. The main defects were the lack of preliminary study design scheme, incomplete search strategy, no list of excluded literature, and no report of included research funding sources, etc. Only 1 of the outcome indicators was classified as high quality, 7 were classified as intermediate, and the rest were low or very low quality.Conclusions:Methodological quality and strength of evidence of systematic reviews/meta-analysis on the effectiveness of non-pharmaceutical intervention for CINV are generally low, and the reliability of research results is poor. It is necessary to design scientific and rigorous high-quality RCTs and systematic reviews to further verify the effectiveness of non-pharmaceutical interventions in the future.
