Research progress of cystic fibrosis associated Pseudo-Bartter syndrome
10.3760/cma.j.cn101070-20220130-00118
- VernacularTitle:囊性纤维化并假性Bartter综合征研究进展
- Author:
Zhiao DU
1
;
Huiming SUN
;
Zhengrong CHEN
Author Information
1. 苏州大学附属儿童医院呼吸科，苏州 215003
- Keywords:
Cystic fibrosis;
Pseudo-Bartter syndrome;
Cystic fibrosis transmembrane conductance regulator
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(22):1727-1729
- CountryChina
- Language:Chinese
-
Abstract:
Cystic fibrosis (CF) is an autosomal recessive inherited disease affecting multiple body systems.Pseudo-Bartter syndrome (PBS) is a common manifestation of CF, with such clinical features as hypochloremia, hyponatremia, hypokalemia and metabolic alkalosis.However, PBS patients do not have renal tubulopathy.Children with CF are prone to develop electrolyte abnormalities due to fluid and electrolyte loss.In this article, the pathogenesis, clinical manifestations, diagnosis, and treatment of CF associated PBS were reviewed in order to enhance clinical understan-ding of this disease.
