Research status of intestinal flora and pathogenesis of epilepsy

VernacularTitle:肠道菌群与癫痫发病机制的研究现状
Author: Nanfei HU ¹ ; Jun QIU ; Lihong TAN
Author Information

1. 南华大学儿科学院，湖南省儿童医院神经内科，长沙　410007
Keywords: Intestinal flora; Epilepsy; Pathogenesis
From: Chinese Journal of Applied Clinical Pediatrics 2022;37(20):1589-1592
CountryChina
Language:Chinese
Abstract: Epilepsy is a chronic brain dysfunction caused by the excessive synchronous firing of neurons.It is one of the common nervous system diseases in children.Repeated epileptic seizures often lead to physiological and inte-llectual damage in children, seriously affecting children′s growth, development and health.Previous studies have shown that there are significant differences in intestinal flora between epileptic and normal children.Intestinal flora participate in the development of epilepsy through multiple pathways, including the immune system, hypothalamic-pituitary-adrenal axis, neurotransmitters and vagus nerve.