Research progress on neurodevelopmental disorders in children with Duchenne muscular dystrophy
10.3760/cma.j.cn101070-20210723-00870
- VernacularTitle:Duchenne型肌营养不良患儿共患神经发育障碍研究进展
- Author:
Xinying YANG
1
;
Junlan LYU
Author Information
1. 国家儿童医学中心，首都医科大学附属北京儿童医院神经内科，北京 100045
- Keywords:
Duchenne muscular dystrophy;
Neurodevelopmental disorder;
Comorbidity
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(19):1516-1520
- CountryChina
- Language:Chinese
-
Abstract:
Duchenne muscular dystrophy (DMD) is a disease inherited in an X-linked recessive pattern, which is caused by the pathogenic mutation of the gene encoding Dystrophin.An increasing number of studies have confirmed the high risk of neurodevelopmental disorders in children with DMD, and that related comorbidities have distinct clinical characteristics.In this article, the research progress on neurodevelopmental disorders in children with DMD was reviewed to clarify the prevalence, clinical characteristics and high-risk factors of neurodevelopmental disorders in children with DMD.DMD therapy teams should pay attention to the evaluation, interpretation and early intervention of neurodevelopmental disorders in clinic practice, so as to improve the life quality of DMD children and help them to be-tter integrate into the society.
