Thrombolytic therapy for 2 children with Mycoplasma pneumoniae pneumonia complicated with intracardiac thrombosis and pulmonary embolism
10.3760/cma.j.cn101070-20211109-01332
- VernacularTitle:溶栓治疗儿童肺炎支原体肺炎并心腔血栓及肺栓塞2例
- Author:
Chunjuan DONG
1
;
Yongsheng XU
;
Jing NING
;
Hanquan DONG
;
Fangfang SHEN
;
Ya FU
Author Information
1. 天津市儿童医院呼吸科，天津 300134
- Keywords:
Mycoplasma pneumoniae;
Pulmonary embolism;
D-dimer;
Thrombolysis;
Intracardiac thrombosis
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(19):1495-1497
- CountryChina
- Language:Chinese
-
Abstract:
The clinical data of 2 children with refractory Mycoplasma pneumoniae pneumonia complicated with intracardiac thrombosis and pulmonary embolism, treated in Tianjin Children′s Hospital from July 2019 to January 2020, were analyzed retrospectively.One patient was an 8-year-old girl, who was admitted to the hospital mainly because of " fever for 5 days and cough for 2 days" . The other patient was a 7-year-old boy, who was admitted due to " intermittent fever with cough for 24 days and chest pain for 1 day" . Both children were complicated with elevated D-dimer levels and positive antiphospholipid antibody.During the treatment, right cardiac thrombosis and pulmonary embolism occurred in both cases, and the manifestations of thrombosis related symptoms were not typical.After the patients received anticoagulation treatment and thrombolytic therapy with urokinase, the cardiac thrombus dissipated and the pulmonary embolism improved.For refractory Mycoplasma pneumoniae pneumonia complicated with intracardiac thrombosis and pulmonary embolism, thrombolytic therapy can be applied to some children in addition to anticoagulant therapy.
