Relationship between intestinal flora and brain development in premature infants
10.3760/cma.j.cn101070-20210317-00317
- VernacularTitle:早产儿肠道菌群与大脑发育的关系
- Author:
Jin SUN
1
;
Panpan YU
;
Shiyi SONG
;
Yunfeng ZHANG
;
Xin TIAN
Author Information
1. 吉林大学第二医院儿科诊疗中心，长春 130000
- Keywords:
Infant, premature;
Neurodevelopment;
Microbiome
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(17):1358-1360
- CountryChina
- Language:Chinese
-
Abstract:
Preterm delivery caused by various reasons leads to intestinal flora dysplasia in premature infants.In the early stages of life, there is a parallel development window between the intestinal microflora and the nervous system.Premature infants represent a unique population, whose brain development can be influenced by early microbial colonization.Microbiota optimization can improve the development of the nervous system.In this article, factors affecting the intestinal flora of premature infants, the effects of intestinal flora imbalance on the nervous system development, and the impact of early addition of probiotics on the development of premature infants were reviewed.Understanding the role of early optimization of the microbiota in the brain development of premature infants is essential for developing specific treatments for intestinal microbiota imbalance and protecting premature infants from a series of neurodevelopmental disorders caused by preterm delivery.
