The effect of artificial oocyte activation on the short- and long-term development of offspring
10.3760/cma.j.cn101070-20210310-00284
- VernacularTitle:卵母细胞人工激活技术对子代近、远期发育的影响
- Author:
Shuming SHAO
1
;
Yimin ZHANG
;
Xiaorui ZHANG
;
Fang FANG
;
Qun LU
;
Jie LIU
;
Chaomei ZENG
Author Information
1. 北京大学人民医院儿科，北京 100044
- Keywords:
Artificial oocyte activation;
Offspring;
Effect
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(17):1355-1357
- CountryChina
- Language:Chinese
-
Abstract:
Intracytoplasmic sperm injection (ICSI) is an important treatment option for male infertility at pre-sent.However, a few patients still suffer from repeated ICSI fertilization failure because their sperm is unable to activate oocytes.Artificial oocyte activation (AOA) technology can improve the fertilization rate, pregnancy rate, live birth rate, etc., but it remains unknown whether AOA has short- and long-term effect on offspring.In this article, recent literature about the effect of AOA technology on perinatal outcomes, genetics, physical development and neurological development of offspring was summarized.This paper aims to provide reference for reproductive medicine workers and pediatricians in clinical practice.
