Research progress of the exosomes in diagnosis and treatment of central nervous system diseases
10.3760/cma.j.cn101070-20210204-00160
- VernacularTitle:外泌体在中枢神经系统疾病诊治中的研究进展
- Author:
Junwen GE
1
;
Li SHEN
Author Information
1. 上海交通大学医学院附属儿童医院，上海市儿童医院心胸外科，上海 200062
- Keywords:
Exosome;
Central nervous system;
Diagnosis;
Treatment;
Progress
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(13):1034-1037
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are some small membrane-bound vesicles released by cells into extracellular spaces.They carry a variety of bioactive molecules, such as proteins, RNA and lipids for material exchange and communication in cells.Exosomes have been recognized as an important pathway in the nervous system in both normal and disease settings.Meanwhile, exosomes can pass through the blood-brain barrier.Therefore, exosomes provide a new strategy for the diagnosis and treatment of central nervous system diseases.In this review, general characteristics of exosomes, pathological and physiological functions of exosomes in central nervous systems and the progress of exosomes applied to the diagnosis and treatment of central nervous system diseases are discussed.
