Bullae-Forming Pulmonary Metastasis from Choriocarcinoma Presenting as Pneumothorax.
10.5090/kjtcs.2015.48.6.435
- Author:
Kwanyong HYUN
1
;
Hyeon Woo JEON
;
Kyung Soo KIM
;
Kook Bin CHOI
;
Jae Kil PARK
;
Hyung Joo PARK
;
Young Pil WANG
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Korea. ypwang@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Pneumothorax;
Choriocarcinoma;
Lung metastasis;
Chemotherapy
- MeSH:
Adult;
Choriocarcinoma*;
Chorionic Gonadotropin;
Consolidation Chemotherapy;
Diagnosis, Differential;
Drug Therapy;
Early Diagnosis;
Female;
Fertility;
Follow-Up Studies;
Gestational Trophoblastic Disease;
Humans;
Hydatidiform Mole, Invasive;
Lung;
Neoplasm Metastasis*;
Pneumothorax*;
Pregnancy;
Trophoblastic Tumor, Placental Site;
Trophoblasts;
Uterus
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2015;48(6):435-438
- CountryRepublic of Korea
- Language:English
-
Abstract:
Gestational trophoblastic disease (GTD) is a condition of uncertain etiology, choriocarcioma, or placental-site hydatidiform moles, invasive moles, choriocarcinoma, and placental-site trophoblastic tumors. It arises from the abnormal proliferation of trophoblastic tissue and spreads beyond the uterus hematogenously. The early diagnosis of GTD is important to ensure timely and successful management and the preservation of fertility. We report the unusual case of a metastatic choriocarcinoma that formed bullae on the lung surface and presented as recurrent pneumothorax in a 38-year-old woman with elevated beta-human chorionic gonadotropin (hCG) levels. She underwent thoracoscopic wedge resection of the involved lung and four subsequent cycles of consolidation chemotherapy. No other evidence of metastatic disease or recurrent pneumothorax was noted during 22 months of follow-up. GTD should be considered in the differential diagnosis of spontaneous pneumothorax in reproductive-age women with an antecedent pregnancy and abnormal beta-hCG levels.
