Analysis of demographic and clinical characteristics of 1668 patients with different types of hyperglycemic crisis
10.3760/cma.j.cn.115807-20211203-00370
- VernacularTitle:1 668例不同类型高血糖危象患者人口学及临床特征分析
- Author:
Rui HE
1
;
Hong LI
;
Kebiao ZHANG
;
Manping GU
Author Information
1. 重庆医科大学附属第一医院急诊科,重庆 400016
- Keywords:
Hyperglycemic crisis;
Diabetic ketoacidosis;
Hyperglycemic hyperosmolar state;
Clinical feature;
Diabetes mellitus
- From:
Chinese Journal of Endocrine Surgery
2022;16(4):473-478
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze and compare the demographic and clinical characteristics of patients with different types of hyperglycemic crisis, so as to provide clinical basis for the prevention and treatment of hyperglycemic crisis.Methods:The data of patients with hyperglycemic crisis in six First-level general hospitals in Chongqing from Jan. 2015 to Dec. 2020 were retrospectively collected and divided into diabetic ketoacidosis (DKA) , hyperglycemic hyperosmolar state (HHS) and diabetic ketoacidosis with hyperglycemic hyperosmotic state (DKA-HHS) . The demographic and clinical characteristics of each group were analyzed by descriptive method.Results:A total of 1668 patients were collected, among whom1388 were DKA, 113 were HHS and 167 were DKA-HHS. The proportion of T2DM in DKA was 90.1%, the proportion of urban residents’ medical insurance, farmers and retirees was higher in the three groups, and the incidence of hyperglycemic crisis in patients above 60 years old was the highest in all age groups. The incidence of DKA and HHS changed little during the six years, but increased significantly in the DKA-HHS group. Shock, disturbance of consciousness, hospitalization expenses and mortality in the DKA-HHS group were higher than those in the other two groups.Conclusions:There are differences in demographic and clinical characteristics among different types of hyperglycemic crisis. Clinically, more attention should be paid to patients above 60 years old and patients with hyperglycemic crisis such as DKA-HHS. Health education and guidance for diabetic patients in high-risk groups should be strengthened in order to reduce the occurrence of diabetic hyperglycemic crisis.