Spontaneous Cerebral Microbleeds on Gradient Echo MR Imaging in the Stroke Patients.
10.3348/jkrs.2003.49.2.77
- Author:
Seong Ho KWAK
1
;
Chang June SONG
;
Dae Bong KIM
;
Geum Chae JEONG
Author Information
1. Department of Radiology, Chungnam National University College of Medicine.
- Publication Type:Original Article
- Keywords:
Brain, hemorrhage;
Brain, MR;
Hemorrhage, MR
- MeSH:
Basal Ganglia;
Brain Stem;
Cerebellum;
Cerebral Hemorrhage;
Corpus Callosum;
Diabetes Mellitus;
Female;
Heart Diseases;
Humans;
Hypertension;
Incidence;
Infarction;
Magnetic Resonance Imaging*;
Male;
Retrospective Studies;
Risk Factors;
Stroke*;
Stroke, Lacunar;
Thalamus
- From:Journal of the Korean Radiological Society
2003;49(2):77-83
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the spontaneous cerebral microbleeding occurring at gradient-echo MRI, and its relationship with associated stroke lesions and risk factors. MATERIALS AND METHODS: Between September 2001 and December, 2002, 32 patients (21 men and 11 women; mean age 63 years) in whom cerebral microbleeding occurred at gradient-echo MRI were retrospectively investigated. Using a 1.5 T MR imager, spin-echo T1-weighted, fast spin-echo T2-weighted, diffusion-weighted, and gradient-echo images were obtained. The number and location of microbleeds seen on gradient echo images, patient data, and associated stroke lesions such as intracerebral hemorrhage and lacunar and territorial infarction were assessed. RESULTS: Among the 32 patients, 563 microbleeds and between 1 and 66 (mean, 17.6) were noted at gradientecho imaging. Microbleeding occurred in the cortical/subcortical area (n=216), the basal ganglia (n=173), thalamus (n=92), cerebellum (n=41), brainstem (n=36) and corpus callosum (n=1), and in 20 patients was bilateral. Patients had a history of hypertension (n=26), hypertriglycemia (n=12), heart disease (n=4), and diabetes mellitus (n=3). Stroke lesions were seen in 27 patients, intracerebral hemorrhage in ten, lacunar infarction in 24, and territorial infarction in four. CONCLUSION: The incidence and number of microbleeds was greater in older patients and in those with hypertension, hypertriglycemia, and stroke lesions such as intracerebral hemorrhage or lacunar infarction. The detection of microbleeding at gradient-echo imaging is helpful, since it predicts the possibility of cerebral hemorrhage in these patients.
