Effect of early external diaphragm pacing on patients with mechanical ventilation
10.3760/cma.j.issn.1671-0282.2022.06.018
- VernacularTitle:早期体外膈肌起搏对机械通气患者的影响研究
- Author:
Jieying LUO
1
;
Xiaotong HAN
;
Shuzhen MAO
;
Maiying FAN
;
Xiquan YAN
;
Hui WEN
;
Zhou ZHOU
;
Yan CAO
;
Yucheng ZHOU
Author Information
1. 湖南省人民医院（湖南师范大学附属第一医院）急诊医学科，湖南省急救研究所，湖南省急危重症临床医学研究中心，长沙 410005
- Keywords:
Mechanical ventilation;
External diaphragm pacing;
Diaphragm ultrasound;
Diaphragm dysfunction;
Pulmonary rehabilitation;
Diaphragm thickness;
Diaphragm exc
- From:
Chinese Journal of Emergency Medicine
2022;31(6):798-803
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of early external diaphragm pacing on the diaphragm function and prognosis of patients with mechanical ventilation.Methods:A total of 47 patients receiving invasive mechanical ventilation in the Emergency Intensive Care Unit of Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University) from October 2019 to July 2021 were selected and randomly divided into the treatment group ( n=23) and control group ( n=24). The patients in the control group received routine clinical treatment. On this basis, the treatment group received external diaphragm pacing treatment every day from the third day of mechanical ventilation until weaning, and was followed up to 30 days after discharge. The diaphragm thickness, diaphragm excursion, diaphragm thickening fraction, mechanical ventilation time, number of weaning failures, length of hospital stay and death toll were compared between the two groups. Results:Compared with the control group, the diaphragm thickness [(0.21±0.05) cm vs. (0.16±0.05) cm], diaphragm excursion [(1.38±0.37) cm vs. (1.11±0.48) cm], and diaphragm thickening fraction [26% (19%, 32%) vs. 18.5% (10.25%, 20%)] in the treatment group increased significantly (all P<0.05). The mechanical ventilation time was shorter in the treatment group [10 (7, 15) d vs. 13 (10.25, 19) d], and the difference was statistically significant ( P<0.05). There were no significant differences in the number of weaning failures (7 vs. 9), length of hospital stay [22 (15 , 30) d vs.. 24 (17.25, 34.25) d] and deaths (8 vs. 8) (all P>0.05). Conclusions:Early application of external diaphragm pacing can improve the diaphragm function of patients with mechanical ventilation, delay the decline in diaphragm function, increase diaphragm excursion and diaphragm thickening fraction, and shorten the mechanical ventilation time.
